Course Syllabus

 

PLSC 751 Syllabus
Spring Semester 2005


1. Understanding probability
2. Statistical distributions
   A. chi-square
   B. normal
   C. poisson
3. Meiosis and cross-overs
4. Linkage analysis
   A. chi-square for linkage
   B. recombinant fraction estimation
   C. concepts
   D. maximium likelihood estimation
   E. combining linkage estimates
   F. Fisher's scoring method
5. Double crossovers and gene mapping
   A. three-point testcross
   B. interference
6. Planning experiments
   A. minimium family size
   B. marker coverage to identify QTL's
   C. distinquishing between two-class segregations
   D. prediction of marker coverage and map density
7. LOD score
   A. independent events
   B. plotting LOD scores
   C. marker assisted selection
      a. effectiveness as linkage increases
      b. position and effect are confounded
      c. concepts
8. Polyploidy and anueploidy
   A. double reduction
   B. maximial equational segregation
   C. chromosome segregation ratio
   D. self-fertilization genetic ratios of autotetraploids
9. Linkage in autotetraploids

Copyright 2000©, Ted Helms

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