Likelihood Ratio Test For Discrete Classes

LOD Score

Example

Varying Q

Maximum Likelihood: Testcross Data

Plotting Lod Scores

Homework Assignment # 9 Questions

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Likelihood Ratio Test For Discrete Classes

See Liu, Statistical Genomics: Linkage, Mapping, and QTL Analysis. pgs 99-100.

"The ratio between the likelihood of Q taking a value QA, which maximizes the likelihood, e.g. a maximum likelihood estimator and the likelihood of Q under the null hypothesis QN, e.g. QN = 0.5 is:    L(QA/X "
       L(QN/X)

Likelihood ratio test statistic = G
= -2ln [ l(QA|x) ]  
l(QN|x)      

G has an appropriate X2 distribution.

Copyright 2000©, Ted Helms

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